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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
8.48
Human Site:
S1216
Identified Species:
14.36
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
S1216
N
L
P
L
D
H
A
S
L
V
K
S
W
P
E
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
S1216
N
L
P
L
D
H
A
S
L
V
K
S
W
P
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
E895
L
V
K
S
W
P
E
E
V
S
R
G
G
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
Q1421
G
L
S
L
S
S
P
Q
V
P
G
S
P
F
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
V852
P
K
R
S
P
P
A
V
L
A
L
N
V
P
Q
Chicken
Gallus gallus
Q5F3P8
2008
223067
S1378
Q
L
M
V
T
K
T
S
I
E
E
E
I
P
R
Frog
Xenopus laevis
Q66J90
1938
216239
T1410
P
G
R
D
F
N
F
T
P
I
F
P
E
S
N
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
S1289
T
V
P
V
T
P
G
S
D
T
P
L
T
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
A1166
T
R
S
C
F
E
S
A
S
K
V
D
T
T
L
Honey Bee
Apis mellifera
XP_395451
1406
159180
L971
T
D
S
E
E
E
S
L
E
I
R
R
L
R
Y
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
E1072
P
Y
K
I
V
H
W
E
K
A
G
I
I
E
M
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
D1465
S
D
I
E
S
D
E
D
W
T
E
S
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
M645
L
S
N
G
I
K
P
M
A
H
L
L
N
E
E
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
K878
K
A
E
P
A
E
D
K
E
T
E
D
S
R
L
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
0
N.A.
20
N.A.
N.A.
20
20
0
13.3
N.A.
0
0
6.6
6.6
P-Site Similarity:
100
100
N.A.
20
N.A.
26.6
N.A.
N.A.
33.3
40
20
26.6
N.A.
13.3
26.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
22
8
8
15
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
8
15
8
8
8
8
0
0
15
0
0
0
% D
% Glu:
0
0
8
15
8
22
15
15
15
8
22
8
8
15
22
% E
% Phe:
0
0
0
0
15
0
8
0
0
0
8
0
0
8
0
% F
% Gly:
8
8
0
8
0
0
8
0
0
0
15
8
8
8
0
% G
% His:
0
0
0
0
0
22
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
8
8
0
0
0
8
15
0
8
15
0
0
% I
% Lys:
8
8
15
0
0
15
0
8
8
8
15
0
0
0
0
% K
% Leu:
15
29
0
22
0
0
0
8
22
0
15
15
8
0
15
% L
% Met:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
8
% M
% Asn:
15
0
8
0
0
8
0
0
0
0
0
8
8
0
15
% N
% Pro:
22
0
22
8
8
22
15
0
8
8
8
8
8
29
0
% P
% Gln:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% Q
% Arg:
0
8
15
0
0
0
0
0
0
0
15
8
0
22
8
% R
% Ser:
8
8
22
15
15
8
15
29
8
8
0
29
15
15
22
% S
% Thr:
22
0
0
0
15
0
8
8
0
22
0
0
15
8
0
% T
% Val:
0
15
0
15
8
0
0
8
15
15
8
0
8
0
0
% V
% Trp:
0
0
0
0
8
0
8
0
8
0
0
0
15
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _